a957@phase-space:~$

biology (dynamical system)

Research themes

Cell fate & transcriptomic dynamics

How does a cell commit to what it becomes? I think about this with the tools of dynamical systems (attractors, basins, vector fields) applied to RNA expression. A cluster label tells you where a cell sits. I want a picture that also says which way it is being pushed, and which fates are still open to it (and how hard it would be to get there).

Behavioral phenotyping & machine learning

At JAX I led JABS (the JAX Animal Behavior System, with Vivek Kumar's lab). It is an open platform that takes you from video of a mouse to its pose, then to behavior classifiers, and finally to genetics. A lot of the work is in the plumbing between those steps, and the part I care about most is making it something other labs actually pick up and use.

Physics-aware scientific machine learning

At NC State (with William Ditto, John Lindner and Sudeshna Sinha) I asked a simple question: if a neural network knows the structure of the physics (energy conservation, the geometry of phase space), does it forecast better? For Hamiltonian systems it mostly did, and the gain was largest where ordinary networks get lost (through the order-to-chaos transition and across separatrices). We also looked at how this scales with data and dimension, and found that letting neurons differ from each other helps learning too.

Dynamics on complex networks

My PhD (at IISER Mohali) and first postdoc (at Oldenburg) were about dynamics on networks, mostly coupled oscillators. The wiring (fixed, rewired over time, or small-world) decides whether they fall into step. I spent a lot of time on how far a synchronized network can be pushed before it stops coming back (basin stability for many nodes at once, and recovery times after local shocks). At Oldenburg I moved to synchronization in ecological food webs, and to a curious case where weakly coupled units lock in phase while the strongly coupled ones keep drifting.

Papers

Google Scholar

01Cell fate

  1. MorPhiC Consortium: towards functional characterization of all human genes

    MorPhiC Consortium (A. Choudhary is a consortium member)

    Nature, 2025

02Behavior & genetics

  1. JAX Animal Behavior System (JABS): A genetics-informed, end-to-end advanced behavioral phenotyping platform for the laboratory mouse

    A. Choudhary, B. Q. Geuther, T. J. Sproule, G. Beane, V. Kohar, J. Trapszo, V. Kumar

    eLife, 2025

03Physics-informed ML

  1. Neuronal diversity can improve machine learning for physics and beyond

    A. Choudhary, A. Radhakrishnan, J. F. Lindner, S. Sinha, W. L. Ditto

    Scientific Reports, 2023

  2. Forecasting Hamiltonian dynamics without canonical coordinates

    A. Choudhary, J. F. Lindner, E. G. Holliday, S. T. Miller, S. Sinha, W. L. Ditto

    Nonlinear Dynamics, 2021

  3. Negotiating the separatrix with machine learning

    S. T. Miller, J. F. Lindner, A. Choudhary, S. Sinha, W. L. Ditto

    Nonlinear Theory and Its Applications, IEICE, 2021

  4. Physics-enhanced neural networks learn order and chaos

    A. Choudhary, J. F. Lindner, E. G. Holliday, S. T. Miller, S. Sinha, W. L. Ditto

    Physical Review E, 2020

  5. The scaling of physics-informed machine learning with data and dimensions

    S. T. Miller, J. F. Lindner, A. Choudhary, S. Sinha, W. L. Ditto

    Chaos, Solitons & Fractals: X, 2020

04Dynamics on networks

  1. Weak-winner phase synchronization: A curious case of weak interactions

    A. Choudhary, A. Saha, S. Krueger, C. Finke, E. Rosa, J. A. Freund, U. Feudel

    Physical Review Research, 2021

  2. Suppression and revival of oscillations through time-varying interaction

    S. S. Chaurasia, A. Choudhary, M. D. Shrimali, S. Sinha

    Chaos, Solitons & Fractals, 2019

  3. Multiple-node basin stability in complex dynamical networks

    C. Mitra, A. Choudhary, S. Sinha, J. Kurths, R. V. Donner

    Physical Review E, 2017

  4. Recovery time after localized perturbations in complex dynamical networks

    C. Mitra, T. Kittel, A. Choudhary, J. Kurths, R. V. Donner

    New Journal of Physics, 2017

  5. Small-world networks exhibit pronounced intermittent synchronization

    A. Choudhary, C. Mitra, V. Kohar, S. Sinha, J. Kurths

    Chaos, 2017

  6. Are network properties consistent indicators of synchronization?

    P. D. Rungta, A. Choudhary, C. Meena, S. Sinha

    Europhysics Letters, 2017

  7. Synchronization in time-varying networks

    V. Kohar, P. Ji, A. Choudhary, S. Sinha, J. Kurths

    Physical Review E, 2014

  8. Taming explosive growth through dynamic random links

    A. Choudhary, V. Kohar, S. Sinha

    Scientific Reports, 2014